Researchers found strong evidence of an association between cannabis use disorder and schizophrenia among men and women, though the association was much stronger among young men. Using statistical models, the study authors estimated that as many as 30% of cases of schizophrenia among men aged 21-30 might have been prevented by averting cannabis use disorder.

Young men at highest risk of schizophrenia linked with cannabis use disorder

NIH study highlights the need to proactively screen for, prevent, and treat cannabis use disorder especially among young people.

Drug-Induced Psychoses May Signal Substantial Schizophrenia Risk

More than a third of people who experienced psychosis with cannabis use later transitioned to schizophrenia, according to a systematic review and meta-analysis published online in Schizophrenia Bulletin. Schizophrenia News

Transition to schizophrenia was highest (34%) for cannabis-induced psychoses

Overall 25% of people with substance-induced psychosis were later diagnosed with schizophrenia, compared with 36% of people who first presented with brief, atypical, and not otherwise specified psychoses. Among the 25 studies that looked at substance use-induced psychosis, transition to schizophrenia was highest (34%) for cannabis-induced psychoses.